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 bioengineering, biotechnology, diagnostics, fabrication, analytical chemistry


Key Points:

  • Develop devices for point-of-care analysis.

  • Build technologies that can be used for simple diagnostics and analysis.

  • Make complicated or expensive assays simpler and more accessible.

Detailed Description:

We develop microfluidic or paperfluidic devices for point-of-care analysis.  We take existing and gold-standard analysis methods and develop small-scale, easy-to-use devices for use in low-resource or non-laboratory settings.  We develop readout methods compatible with the analysis that can be assessed visually.  We integrate the analysis and readout method into the devices for a complete device without external pumps, power supplies, or computers.


Key Points:

  • Many places worldwide have limited infrastructure for the “gold-standard” types of analysis (ie: HPLC, GC, PCR, ICP).

  • Rapid, on-site analysis is critical in many situations – ie, to stop the spread of disease (COVID, E. bola), for triage at the site of an incident and in an ambulance, or for responses to environmental disasters.

Detailed Description:

Chemical or bio-analysis is necessary in many situations where a central laboratory is not present nor practical.  Similarly, rapid analysis is necessary for a quick response, whether it be starting proper treatment for a disease or knowing when water is safe to drink.  Our stream’s work has implications in situations including disease diagnosis and tracking and healthcare and environmental analysis in low-resource settings.


Key Points:

  • Technology including Matlab and CAD.

  • Fabrication methods including 3D printing, cutter-plotting, and PDMS molding.

  • Microfluidic design and fluid flow concepts.

  • Point-of-care device design considerations and constraints, and how to design around parameters/goals to be met.


Detailed Description:

Students learn computing methods such as Matlab and CAD, and will gain experience in fabrication methods such as 3D printing, cutter-plotting, and PDMS molding.  Students also learn about microfluidics and fluid flow concepts, along with point-of-care and small-scale device design considerations and constraints.

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