WHAT WE DO
The FIRE Bacterial Pathogenesis stream is interested in understanding how the bacterial opportunistic pathogen Pseudomonas aeruginosa causes a specific type of hospital-acquired infections (HAIs) called catheter-associated urinary tract infections or CAUTI in humans
WHY IT MATTERS
Pseudomonas aeruginosa is a common cause of hospital-acquired infections (HAIs) in the US. HAIs are infections people get while they are receiving healthcare for another condition. HAIs can happen in any health care facility including hospitals, surgical centers, and long-term care facilities. HAIs are an immense burden on the US healthcare system. In 2009, there were an estimated 1.7 million reported HAIs with estimated direct medical costs of 28 to 45 billion dollars annually.
WHAT YOU LEARN
Our lab is interested in identifying genes in Pseudomonas aeruginosa that are important for the bacteria to cause CAUTI. You will learn 1. how to use the scientific method to ask questions and solve problems. 2. general microbiology aseptic techniques: streaking bacterial cultures for isolation, starting bacterial cultures, micro pipetting, and 3. commonly used molecular cloning tools polymerase chain reaction (PCR) and CRISPR-based gene silencing.